ea0031p200 | Obesity, diabetes, metabolism and cardiovascular | SFEBES2013
Hadebe Silindile
, Dube Sinenkosi
, Khathi Andile
, Serumula Metse
, Myburg Rene
, Musabayane Cephas T
The magnitude and duration of postprandial blood glucose elevations due to hydrolysis of carbohydrates are major risk factors of diabetes and coronary heart diseases. Inhibition of the key carbohydrate hydrolyzing enzymes in the small intestine suppresses postprandial blood glucose peaks and reduces chronic vascular complications in diabetic subjects. Recent reports indicate that Syzygium spp-derived oleanolic acid (OA) inhibits glucose transport in the small intestin...